Happy Saffron Plus
Elevate Your Mood. Sharpen Your Mind. Restore Your Rest.
Unlock the power of ancient botanicals and modern science — Happy Saffron Plus fuses premium saffron extract, bio-optimized curcumin, and essential zinc into one clean formula to support emotional balance, cognitive clarity, restful sleep, and overall well-being. Feel calmer, think clearer, and wake up refreshed — naturally.
The BrainMD Promise
Superior Formulas. Exceptional Ingredients. Unmatched Quality.
At BrainMD, we are committed to helping you feel your best through clean, scientifically backed nutrition. Every product is made with all-natural, ethically sourced ingredients — completely free of gluten, wheat, eggs, corn, added sugars, artificial colors or flavors, and the common toxins other brands often ignore, including dioxins.
From sourcing to final packaging, each bottle is rigorously tested and closely monitored to ensure purity, potency, and consistent excellence. And because your well-being is our priority, your purchase is always protected: if you’re not 100% satisfied, we’ll make it right with a full refund.
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BRAIN HEALTH
A 360 approach to optimal brain and physical wellness and purposeful living
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SCIENCE & MEDICAL DATA
Founded and formulated by the best doctors
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PURITY OF INGREDIENTS
Clinical-grade and free of toxins that others may not address
Clinically Researched Benefits
As a company firmly rooted in science, we use only clinically researched ingredients that create real results. Here are some of the benefits of taking the natural mood enhancer Happy Saffron Plus:
- Happier mood*
- Enhanced memory & cognition*
- Improved sexual function*
- Greater resilience to stress*
- Increased focus*
- Decreased feelings of anxiousness*
- Better joint health & mobility*
- More energy*
- Appetite control*
Feel Better. Think Clearer. Live Brighter.
Happy Saffron Plus brings together three powerful, clinically studied nutrients — saffron, Longvida® curcumin, and zinc — in their most bioavailable forms to support mood, memory, sexual function, brain health, and overall well-being.* If you’re feeling emotionally overwhelmed or stuck in a constant up-and-down cycle, this 3-in-1 formula offers natural, targeted support to help restore balance and elevate your everyday health.*
How to Use for Best Results
Daily Use
Take 3 capsules daily between meals for optimal absorption and effectiveness.
Fast-Acting Support
Clinical research shows that 400 mg of Longvida® Curcumin—the same amount in Happy Saffron Plus—can enhance working memory by 16% within just one hour of your first dose.*
Long-Term Benefits
For lasting improvements in mood, emotional balance, and reduced anxiousness, maintain consistent daily use for at least 3 months. Benefits continue to build and strengthen over time.*
Note: Results may vary based on individual health and lifestyle factors. For best outcomes, pair with a balanced diet and regular exercise.*
Total Mind & Mood Support
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Unlock a Happier Brain — and a Healthier You
Saffron has been treasured for thousands of years in Eastern medicine for its potent antioxidant power and natural mood-boosting benefits. Often called the “happiness spice,” saffron is now widely recognized for its ability to elevate mood and ease feelings of anxiousness in both adults and adolescents.*
Its reputation extends beyond emotional wellness — saffron is also celebrated for its natural aphrodisiac properties, making it a key ingredient in many libido-support supplements.* But quality matters. Many saffron products on the market are diluted with fillers, artificial additives, or non-saffron plant material.
That’s why our formula uses pure, clinically studied saffron, delivering the clean, effective support your mind and body deserve.*
Boost Your Mood — Naturally and Safely
Zinc is an essential micronutrient involved in more than 300 enzymatic reactions, supporting everything from energy production and DNA synthesis to antioxidant activity, immunity, and healthy cell development.*
Across six randomized, double-blind, placebo-controlled trials, zinc supplementation has been shown to significantly improve mood in both healthy individuals and those experiencing mood challenges.*
When combined with saffron and curcumin, this powerful trio works synergistically to uplift your mood and support overall well-being — all without unwanted side effects commonly seen with harsher alternatives.*
Formulated to Support: Body & Mind Response • Rest • Focus
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Body & Mind Response*
Designed to help your body and mind respond more effectively to everyday stressors, this formula supports emotional balance, cognitive clarity, and overall resilience. By combining clinically studied saffron, Longvida® curcumin, and essential zinc, it promotes a healthier stress response, steadier mood, and a more centered state of well-being — helping you feel grounded, focused, and supported throughout the day.*
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Rest*
Formulated to support deeper, more restorative rest, this blend helps calm the mind and ease occasional tension so you can unwind naturally. The clinically studied saffron extract works to promote relaxation and improve overall rest quality, helping you wake up feeling refreshed, balanced, and ready for the day ahead.*
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Focus*
Crafted to enhance mental clarity and sustained concentration, this formula supports a sharper, more engaged mind. Longvida® Optimized Curcumin helps reduce mental fatigue and frustration, while saffron’s mood-balancing effects contribute to clearer thinking. Together, they promote a more focused, productive state—so you can stay present, alert, and mentally steady throughout the day.*
• OUR CEO SAYS •
“This is my favorite product I take every day. The ingredients in Happy Saffron Plus are backed by 24 randomized control trials, but the reason I fell in love with this formula is that it supports mood, memory, and sexual function.”
- Daniel G. Amen, MD
Research-Backed & Clinically Proven
Supported by Multiple Peer-Reviewed Studies
Happy Saffron Plus is formulated with ingredients that are extensively validated in modern scientific literature. Numerous randomized, double-blind, placebo-controlled clinical trials demonstrate the effectiveness of saffron, Longvida® Curcumin, and zinc in supporting mood, cognitive function, stress reduction, and overall emotional well-being. These studies span reputable journals in psychopharmacology, nutrition, complementary medicine, and neuroscience, confirming both the safety and the scientifically supported benefits of these ingredients.
Meet Our Founder
Dr. Daniel G. Amen — Leading the Revolution in Brain Health
Dr. Daniel G. Amen, MD, is a world-renowned physician, psychiatrist, and the visionary founder of BrainMD. His mission is to transform mental health by improving brain health worldwide.
He also founded Amen Clinics, one of the most advanced mental health networks in the U.S., with 11 locations and the world’s largest database of over 210,000 brain SPECT scans from 155 countries — offering unparalleled insight into how the brain functions and heals.
As the creator of BrainMD and Amen University, Dr. Amen has trained thousands of healthcare professionals using his brain-based methods. A leading voice in mental wellness, he has millions of followers, produced 17 national public television specials, and created the viral digital series Scan My Brain.
A 12-time New York Times bestselling author, Dr. Amen’s books — including Change Your Brain, Change Your Life and Change Your Brain Every Day — continue to shape the way people improve their mood, memory, focus, energy, and overall well-being.
Why BrainMD
Better Brain. Better Life.
Your brain is the command center for every thought, feeling, and action — and caring for it is essential to your overall success and well-being. At BrainMD, we create science-based nutrition that nourishes the organ that powers everything you do. When your brain receives the support it needs, your mood, energy, clarity, and health all rise with it.
FAQs
What makes BrainMD different?
What makes BrainMD different?
Your brain is central to your overall happiness and success. Feeding your brain properly is essential for optimal fitness and can be the first line of defense in preserving your mental and physical well-being.
With the use of brain SPECT imaging, Dr. Daniel Amen discovered that some prescription medications can damage the brain. He sought out non-toxic solutions for his patients and developed proprietary supplement formulas targeted to memory, mood, focus, and other specific brain functions.
What's BrainMD's "Why"?
What's BrainMD's "Why"?
At BrainMD, we passionately believe that a better brain leads to a better life. We realize the last thing the world needs is another line of poorly-made supplements. From the moment we started operations in 2009, we’ve committed ourselves to providing ultra-pure, clinical-grade, ethically sourced dietary supplements that can supply you with the nutrients you need to lead a brain-healthy life.
We subscribe to a whole-person approach to physical and mental wellness. We’ve dedicated ourselves to helping people feel better by creating the highest quality dietary supplements and nutritional products on the market. The integrity of our work, and our devotion to helping people, inspires our commitment to excellence.
How active is Dr. Amen with your company?
How active is Dr. Amen with your company?
Dr. Amen founded BrainMD and is invested in the ongoing operations and future expansion of the company. He is actively involved in daily management team meetings, weekly strategy meetings, and the development of all new supplements. Dr. Amen is proud of BrainMD’s expansive product line and takes many of the supplements daily.
What supplements would Dr. Amen tell me to try?
What supplements would Dr. Amen tell me to try?
The first step in learning what supplements you should take depends on your specific brain type. Dr. Amen has identified 16 different brain types. Discovering your brain type will help determine a customized supplement regimen.